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Medchemexpress LLC SIRP beta Mouse HE 10ug | 10ug
Supplier: Medchemexpress LLC HYP77490A10UG
SIRP-beta (Sirpb CD172b) is a member of the signal-regulatory-protein (SIRP) family and also belongs to the immunoglobulin superfamily SIRP family members are receptor-type transmembrane glycoproteins Sirpb was found to interact with TYROBP/DAP12 a transmembrane adaptor protein bearing immunoreceptor tyrosine-based activation motifs resulting in the tyrosine phosphorylation of DAP12 and the subsequent recruitment of Syk to the Sirpb-DAP12 complex Sirpb is also implicated as a positive regulator of hematopoietic cells SIRP beta Protein Mouse (HEK293 His) is the recombinant mouse-derived SIRP beta protein expressed by HEK293 with C-His labeled tag
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