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Medchemexpress LLC SIRT-IN-2 | 1431411-66-3 | 98.1% | 383.49 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY16616100MG

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SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50 values of 4, 4, and 7 nM, respectively. This compound is recognized as one of the most potent truncated pan SIRT1/2/3 inhibitors, effectively binding identically in the catalytic active site by occupying the nicotinamide C-pocket and acetyl lysine substrate channel.

  • Potent inhibitor of SIRT1, SIRT2, and SIRT3
  • IC50 values of 4, 4, and 7 nM for SIRT1, SIRT2, and SIRT3, respectively
  • Truncated pan inhibitor
  • Binds identically in the catalytic active site
  • Occupies the nicotinamide C-pocket and acetyl lysine substrate channel

Catalog No. 50-003-93815


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