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Medchemexpress LLC SIRT-IN-2 | 1431411-66-3 | 98.1% | 383.49 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1661650MG

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SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 nM, respectively. It is described as one of the most potent truncated pan SIRT1/2/3 inhibitors. SIRT-IN-2 (compound 31) binds identically in the catalytic active site (RMS=0.29), occupying the nicotinamide C-pocket and acetyl lysine substrate channel.

  • Potent inhibitor of SIRT1/2/3
  • IC50s of 4, 4, 7 nM for SIRT1, SIRT2, and SIRT3
  • Truncated pan SIRT1/2/3 inhibitor
  • Binds in the catalytic active site
  • Occupies nicotinamide C-pocket and acetyl lysine substrate channel

Catalog No. 50-003-93655


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