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Medchemexpress LLC SIRT6 activator 12q | 2601734-99-8 | 99.8% | 454.52 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1487125MG

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SIRT6 activator 12q is a potent, selective, and orally active SIRT6 activator with an IC50 of 0.58 μM for SIRT6. It inhibits cell growth and migration, induces apoptosis and cell cycle arrest at the G2 phase, and demonstrates anticancer activity.

  • Inhibits cell growth and migration
  • Induces apoptosis and cell cycle arrest at the G2 phase
  • Demonstrates anticancer activity
  • Shows antiproliferative activity against human pancreatic cancer cell lines (PANC-1, BXPC-3, MIA PaCa-2, and AsPC-1)
  • Decreases protein expression of H3K9ac, H3K18ac, and H3K56ac in PANC-1 and BXPC-3 cells

Catalog No. 50-003-62305


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