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Medchemexpress LLC SIS17 | 2374313-54-7 | 99.4% | 100 MG
Supplier: Medchemexpress LLC HY128918100MG
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. It is intended for research use only.
- Mammalian histone deacetylase 11 (HDAC 11) inhibitor
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other histone deacetylases
- Suitable for research use
- Inhibits HDAC11 with an IC50 value of 0.83 μM
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Exhibits synergistic cytotoxicity in K562 cells when combined with Oxaliplatin
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