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Medchemexpress LLC Sisomicin sulfate | 53179-09-2 | 99.3% | 100 MG
Supplier: Medchemexpress LLC HYB1222R100MG
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. It exhibits high activity against Gram-positive bacteria. Sisomicin sulfate (6.25 μg/mL) completely inhibits the growth of various clinical isolates of bacteria, such as Klebsiella, Salmonella, Citrobacter, and Staphylococcus aureus. Sisomicin sulfate (20 μg/mL; 30 min) has insignificant impairment on polymorphonuclear neutrophil (PMN). In vivo, Sisomicin sulfate (4 mg/kg; ip; single dose) appears to accumulate and persist in the kidneys, showing potential renal toxicity in rats.
- Broad-spectrum aminoglycoside antibiotic
- Produced by Micromonospora inyoensis
- Highly active against Gram-positive bacteria
- Inhibits the growth of various clinical isolates of bacteria, including Klebsiella, Salmonella, Citrobacter, and Staphylococcus aureus
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