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Cayman Chemical SItamaquIntosylate 10mg
Supplier: Cayman Chemical 3359010 MG
An antileishmanial agent; active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica (EC50s = 9.5-19.8 µM); inhibits SDH in a cell-free assay (10-200 µM); increases intracellular ROS levels, decreases intracellular ATP levels, and induces phosphatidylserine externalization, chromatin fragmentation, and depolarization of the mitochondrial membrane potential in L. donovani promastigotes
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