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Cayman Chemical SItravatInIb 50mg
SDP

Supplier:  Cayman Chemical 2733850 MG

Encompass_Preferred

A group II mGluR agonist (Kis 99 and 94 nM respectively) inhibits forskolin-stimulated cAMP accumulation in cells expressing human mGluR2 and mGluR3 (EC50s 5 1 and 24 3 nM respectively) highly selective for mGluR2 and mGluR3 over mGluR4 mGluR7 mGluR1a and mGluR5a (EC50s 100 UM) suppresses electrically stimulated EPSPs in rat striatal neurons in vitro (EC50 20 nM) suppresses serotonin-induced EPSCs in rat medial prefrontal cortex in vitro (EC50 89 1 nM) attenuates the effects of PCP on working memory stereotypy locomotion and cortical glutamate efflux in a rat model of schizophrenia (10 mg/kg) shows efficacy in animal models of anxiety epilepsy and withdrawal from nicotine and morphine

Catalog No. 50-293-8887


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