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Cayman Chemical SItravatInIb 50mg
Supplier: Cayman Chemical 2733850 MG
A multi-kinase inhibitor; inhibits 35 kinases (IC50s = 0.5-4,098 nM) in a panel of 55 RTKs; reduces proliferation in various cancer cells (IC50s = 340.1-1,830 nM) and decreases phosphorylation of IGF1-R, PDGFRβ, and Akt at 62.5-4,000 nM; decreases tumor growth in LPS141 and MPNST mouse xenograft models at 15 mg/kg per day
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