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Medchemexpress LLC Sj1008030 (formic) | 97.7% | 919.96 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY147330B

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SJ1008030 formic is a JAK2 PROTAC that selectively degrades JAK2. It inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM and can be used for leukemia research. This compound consists of a JAK2 ligand, a Cereblon ligand, and a linker.

  • Selectively degrades JAK2
  • Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM
  • Can be used for the research of leukemia
  • Degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner
  • Dose-dependently degrades JAK2 and GSPT1 protein in xenograft bone marrow SJBALL021415 cells

Catalog No. 50-003-62605


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