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Medchemexpress LLC SJ1008030 formic | 97.7% | 919.96 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY147330B5MG

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SJ1008030 formic is a JAK2 PROTAC that selectively degrades JAK2. It inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM and can be used for leukemia research.

  • Selectively degrades JAK2.
  • Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM.
  • Degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner.
  • Dose-dependently degrades JAK2 and GSPT1 protein in xenograft bone marrow SJBALL021415 cells.
  • Indicates inhibition of the JAK-STAT signaling pathway.
  • Suitable for leukemia research.

Catalog No. 50-003-61420


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