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Medchemexpress LLC SJ1008030 TFA | 2863634-97-1 | 99.8% | 987.96 | 1 MG
Supplier: Medchemexpress LLC HY147330A1MG
SJ1008030 TFA is a JAK2 PROTAC designed for selective degradation of JAK2. This compound inhibits MHH-CALL-4 cell growth and is suitable for leukemia research. It degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner, indicating inhibition of the JAK-STAT signaling pathway.
- Selectively degrades JAK2
- Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM
- Can be used for leukemia research
- Degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner
- Indicates inhibition of the JAK-STAT signaling pathway
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