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Enzo Life Sciences SK&F 96365 (25mg). CAS: 130495-35-1
Supplier: Enzo Life Sciences BMLCA2300025
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells. Alternative name: 1-[beta-[3-(4-Methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole . HCl, SKF-96365 . hydrochloride. Purity: ≥98% (HPLC). Solubility: Soluble in water (30mg/ml). Long Term Storage: Ambient.
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