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Apexbio Technology LLC SKA 31 40172-65-4 100mg
Supplier: Apexbio Technology LLC B7462100
SKA 31 (CAS 40172-65-4) is a small-molecule activator of calcium-activated potassium channels selectively targeting KCa3 1 KCa2 2 KCa2 1 and KCa2 3 subtypes It exhibits EC50 values of 260 nM for KCa3 1 1 9 M for KCa2 2 and 2 9 M for both KCa2 1 and KCa2 3 By facilitating the activation of these channels SKA 31 enhances endothelium-derived hyperpolarizing factor (EDHF) responses This compound is employed to investigate endothelial function and signal transduction with notable utility in studies exploring blood pressure regulation and related vascular mechanisms
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