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Apexbio Technology LLC SKA 31 40172-65-4 100mg
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Supplier:  Apexbio Technology LLC B7462100

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SKA 31 (CAS 40172-65-4) is a small-molecule activator of calcium-activated potassium channels selectively targeting KCa3 1 KCa2 2 KCa2 1 and KCa2 3 subtypes It exhibits EC50 values of 260 nM for KCa3 1 1 9 M for KCa2 2 and 2 9 M for both KCa2 1 and KCa2 3 By facilitating the activation of these channels SKA 31 enhances endothelium-derived hyperpolarizing factor (EDHF) responses This compound is employed to investigate endothelial function and signal transduction with notable utility in studies exploring blood pressure regulation and related vascular mechanisms

Catalog No. 50-000-87789


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