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Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11165550MG

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SKA-31 is a potent potassium channel activator that potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. It is suitable for research use only.

  • Potent potassium channel activator with specific EC50 values for KCa3.1, KCa2.2, KCa2.1, and KCa2.3.
  • Potentiates endothelium-derived hyperpolarizing factor response.
  • Lowers blood pressure.
  • Activates KCa2/3 channels more potently and selectively than other activators.
  • Not acutely toxic and has good pharmacokinetic properties.
  • Stimulates KCa3.1 and KCa2.3 in vascular endothelial cells, increasing acetylcholine-induced endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilation.

Catalog No. 50-004-39944


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