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Medchemexpress LLC Skatole | 83-34-1 | 131.17 | 25 G
Supplier: Medchemexpress LLC 25GHYW007355
Skatole (3-methylindole) is a heterocyclic compound found naturally in the feces of vertebrates and certain plants. It is produced by intestinal bacteria and can induce apoptosis of intestinal epithelial cells by activating aryl hydrocarbon receptors (AhR) and p38. Skatole is also used in the perfume industry and as a flavor additive in ice cream.
- Human endogenous metabolite
- P38 target
- Microbial metabolite
- Aryl hydrocarbon receptor target
- Leads to intestinal epithelial cell apoptosis in a time and dose dependent manner
- Activates AhR and p38
- Reverses the suppression of Irisin on Ang II-evoked proliferation, migration, and phenotypic transformation in VSMCs
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