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Medchemexpress LLC SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) | 320386-54-7 | 98.6% | 100 MG
Supplier: Medchemexpress LLC HY128923100MG
SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It acts as a potent hypoglycemic agent by inhibiting glucose synthesis and also inhibits Asn metabolism, leading to an increase in amino acids and amides.
- Orally active PEPCK inhibitor (Ki: 2-9 μM)
- Potent hypoglycemic agent that inhibits glucose synthesis
- Inhibits Asn metabolism
- Increases amino acids and amides
- Reduces blood glucose in starved rats
- Neutralizes Salbutamol-mediated hyperglycaemia in rabbits
- Reduces pyruvate-induced blood glucose level in rats
- Inhibits C2C12 cell proliferation
- Induces myogenic differentiation of C2C12 cells
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