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Medchemexpress LLC Skf-34288 (hydrochloride) | 320386-54-7 | 98.6% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12892350MG

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SKF-34288 hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It functions as a potent hypoglycemic agent by inhibiting glucose synthesis. Additionally, it inhibits Asn metabolism, leading to an increase in amino acids and amides.

  • Inhibits C2C12 cell proliferation
  • Induces myogenic differentiation of C2C12 cells
  • Reduces mRNA expression of Pck2 and genes associated with serine biosynthesis
  • Reduces blood glucose in starved rats
  • Neutralizes Salbutamol-mediated hyperglycaemia in rabbits
  • Reduces Pyruvate-induced blood glucose level in rats

Catalog No. 50-003-40441


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