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Apexbio Technology LLC SKF38393 HCl 62717-42-4 200mg
Supplier: Apexbio Technology LLC B6030200
SKF38393 HCl is a selective dopamine D1 receptor agonist exhibiting activity through direct binding and stimulation of D1 receptors Activation of D1 receptors primarily induces adenylyl cyclase stimulation and increases cAMP-dependent protein kinase signaling subsequently modulating neuronal differentiation growth and dopamine-mediated functional responses Experimental evidence indicates that SKF38393 administration impacts gene expression patterns related to dopamine receptor-sensitive neuronal pathways and neuropeptides Additionally in vitro studies report SKF38393 to inhibit proliferation of certain tumor cell lines exemplified by decreased cell growth in breast carcinoma-derived MCF-7 cells at submicromolar concentrations It is widely utilized as a pharmacological tool in neuroscience and oncology research
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