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Medchemexpress LLC SKF89976A hydrochloride | 85375-15-1 | 98.7% | 371.90 | C22H26ClNO2 | 50 MG
Supplier: Medchemexpress LLC HY100228A50MG
SKF89976A hydrochloride is a selective inhibitor of the GABA transporter GAT-1 used in research to probe GABA uptake and transporter pharmacology. It exhibits high potency at GAT-1 with markedly lower potency at GAT-2 and GAT-3, and shows weak activity at monoamine transporters. Supplied as a solid for in vitro and in vivo preclinical studies.
- Selective GAT-1 inhibition with IC50 0.28 μM.
- Lower potency at GAT-2 and GAT-3 (IC50 137.34 μM and 202.8 μM).
- Weak activity at SERT, NET, and DAT consistent with transporter profiling.
- High purity solid suitable for biochemical assays (98.73%).
- Usable in both in vitro transporter assays and preclinical in vivo models.
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