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Medchemexpress LLC SLB1122168 formic | 2999629-17-1 | C23H37N3O3 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY150254A50MG

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SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It leads to a dose-dependent decrease in circulating lymphocytes, and in rats, it achieves a maximum concentration of 4 μM at 2 hours post-dose, maintaining levels ≥1 μM for 24 hours with a half-life of 8 hours.

  • Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
  • Induces a dose-dependent decrease in circulating lymphocytes
  • Relevant for research in respiratory disease, inflammation or immune system disease, pulmonary disease, and lung fibrosis
  • Acts on inflammation/immunology signaling pathways, GPCR/G protein, and LPL receptor

Catalog No. 50-003-73999


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