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Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 5 MG
Supplier: Medchemexpress LLC HY150254A5MG
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. This compound is for research use only. In vivo, it causes a dose-dependent decrease in circulating lymphocytes. In rats, at 10 mg/kg, SLB1122168 reaches a maximum concentration of 4 μM at 2 hours post-dose, maintains levels at ≥1 μM for 24 hours, and has a half-life of 8 hours.
- Potent Spns2-mediated S1P release inhibitor
- IC50 of 94 nM
- Causes a dose-dependent decrease in circulating lymphocytes
- Suitable for research applications
- Demonstrates sustained in vivo activity with levels ≥1 μM for 24 hours
- Half-life of 8 hours in rats
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