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Medchemexpress LLC SM-433, a Smac mimetic | 1071992-81-8 | 99.0% | 561.71 g/mol | C32H43N5O4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1380595MG

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SM-433 is a Smac mimetic small molecule that inhibits inhibitor of apoptosis proteins (IAPs), with reported binding to the XIAP BIR3 domain and cellular activity in cancer cell lines. Supplied as a solid for research use.

  • Functions as a Smac mimetic and IAP inhibitor.
  • Binds XIAP BIR3 with reported IC50 ~1 μM.
  • Shows cellular activity (IC50s <10 μM) in select cancer cell lines.
  • Chemical formula C32H43N5O4; molecular weight 561.71 g/mol.
  • High purity (~99%) and supplied as a white to off-white solid.
  • Soluble in DMSO (160 mg/mL); in vivo formulation protocols available.
  • Storage: keep sealed at 4°C; in solvent store at -80°C long term.

Catalog No. 50-002-22711


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