Thermo Scientific™ SMART Digest™ OligoSelect™ Kit (Magnetic WAX Bead Format)

Catalog No.	Enzyme
03-050-600	Proteinase K

Catalog No. 03-050-600 Supplier Thermo Scientific™ Supplier No. 60190101

Description

Thermo Scientific™ SMART Digest™ OligoSelect Kits enable efficient disruption of protein-nucleotide binding and extraction of oligonucleotide-based drugs and metabolites from biofluids and tissues for accurate quantitation by LC-MS. This kit includes all necessary enzymes, buffers, and solid phase extraction (SPE) materials.

The SMART Digest™ OligoSelect Kit provides a streamlined solution for the disruption of protein-nucleotide binding and extraction of oligonucleotide-based drugs and metabolites from biofluids and tissues, ensuring precise quantitation by LC-MS. This kit includes all essential enzymes, buffers, and extraction materials, offering a comprehensive and reliable choice for your laboratory needs.

• Efficiently disrupts protein-nucleotide binding and extracts oligonucleotide-based drugs and metabolites from biofluids
• Ensures precise quantitation by LC-MS
• Includes all necessary enzymes for effective protein digestion
• Comes with required buffers for optimal enzyme activity
• Features magnetic WAX beads for high-throughput sample processing
• Comprehensive kit designed to streamline your workflow

Specifications

• Bed Weight: 5 mg
• Capture: None
• Cleavage: Proteinase K preferentially cleaves peptide bonds at the carboxylic side of aliphatic and aromatic amino acids
• Enzyme: Proteinase K
• Format: Magnetic
• For Use With (Application): Efficient disruption of protein-nucleotide binding followed by extraction of oligonucleotide-based drugs and metabolites from biofluids and tissues prior to LC-MS quantitation.
• For Use With (Equipment): Universal
• Particle Size: 30 to 70 μm
• Product Line: SMART Digest
• Sorbent: Mixed Mode Weak Anion Exchanger, Polymeric
• Type: Oligo Isolation
• Volume (Metric): 1 mL
• Volume (Metric) Well: 1 mL
• Includes: SMART Digest Soluble Proteinase K (0.5 mL 20 mg/mL), Proteinase K Digest Buffer (25 mL), Magnetic WAX beads 96 well (5 mg/well), WAX Elution Buffer (25 mL)