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Medchemexpress LLC SMI-4a (TCS-PIM-1-4a) | 438190-29-5 | 99.85% | 273.23 | 100 MG
Supplier: Medchemexpress LLC HY16576A100MG
SMI-4a (TCS-PIM-1-4a) is a potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. It also inhibits Pim-2 (IC50 of 100 μM) but does not significantly inhibit other serine/threonine or tyrosine kinases. SMI-4a exhibits anticancer activity. It is for research use only and not sold to patients.
- Potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor
- Inhibits Pim-2
- Has anticancer activity
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