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Medchemexpress LLC SMI-4a (TCS-PIM-1-4a) | 438190-29-5 | 99.9% | 273.23 | 1 ML
Supplier: Medchemexpress LLC HY16576A10MM/1ML
SMI-4a (TCS-PIM-1-4a) is a potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. It also inhibits Pim-2 (IC50 of 100 μM) but does not significantly inhibit other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity.
- Potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor.
- Inhibits Pim-2.
- Has anticancer activity.
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