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Medchemexpress LLC SMS2-IN-2 | 2241838-28-6 | 98.0% | 369.78 | 100 MG
SDP

Catalog No. 5000436641
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SMS2-IN-2 is a potent, highly selective, and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM for SMS2 and 56 μM for SMS1. This compound also demonstrates anti-chronic inflammatory activity.

  • Potent and highly selective SMS2 inhibitor
  • Orally active compound
  • Exhibits anti-chronic inflammatory activity
  • Reduces chronic inflammation in db/db mice
  • Reduces IL-6 and insulin levels in T2DM db/db mouse model

Catalog No. 50-004-36641 Supplier Medchemexpress LLC Supplier No. HY112713100MG
May include imposed supplier surcharges.
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SMS2-IN-2 is a potent, highly selective, and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM for SMS2 and 56 μM for SMS1. This compound also demonstrates anti-chronic inflammatory activity.

  • Potent and highly selective SMS2 inhibitor
  • Orally active compound
  • Exhibits anti-chronic inflammatory activity
  • Reduces chronic inflammation in db/db mice
  • Reduces IL-6 and insulin levels in T2DM db/db mouse model

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