Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000202244

Medchemexpress LLC SN38-COOH | 2170118-23-5 | 96.1% | 492.48 g/mol | C26H24N2O8 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15301310MG

Encompass_Preferred

SN38-COOH is a carboxylated derivative of SN-38, the active metabolite of the topoisomerase I inhibitor irinotecan, supplied as a research reagent for the synthesis of antibody-drug conjugates (ADCs) and conjugation chemistry. It is provided as a powder with specified storage and solubility profiles for in vitro and in vivo use.

  • Carboxylated SN-38 derivative for ADC synthesis.
  • Molecular formula C26H24N2O8; molecular weight 492.48 g/mol.
  • CAS number 2170118-23-5.
  • Purity 96.1%.
  • Storage: powder -20°C (stable up to 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
  • In vitro solubility: DMSO 100 mg/mL with sonication and heating to 60°C.
  • In vivo formulation example provided: 10% DMSO, 40% PEG300, 5% Tween-80, 45% saline (2.5 mg/mL).

Catalog No. 50-002-02244


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.