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Sigma Aldrich Sodium Bis(Trimethylsilyl)Amide Solution

Catalog No. 503081488 Shop All MilliporeSigma Sigma Organic Chemistry Products
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100 mL
4 x 25 mL
800 mL
4 x 100 mL
18 L
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Catalog No. Quantity
50-308-1488 4 x 100 mL
24-558-525ML 4 x 25 mL
24-558-5100ML 100 mL
24-558-5800ML 800 mL
24-558-518L 18 L
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Catalog No. 50-308-1488 Supplier Sigma Aldrich Supplier No. 2455854X100ML
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Sodium bis(trimethylsilyl)amide solution (NaHMDS) is widely used as a strong base in organic synthesis for deprotonation reactions and base-catalyzed reactions. It is also involved in the generation of enolates, Wittig reagents and carbenes.NaHMDS can be used as a base: In the synthesis of N-boc-1-amino-1,3-diene derivatives from N-boc-1-amino-4-methoxy-2-alkenes via 1,4-elimination reactions. To deprotonate alkyl or aryl ketones to generate enolate derivatives by hydroxylation reaction. In the enantioselective synthesis of 1,2-amino alcohols by the reaction between various nitroalkanes and aldehydes via nitroaldol reaction promoted by bimetallic heterogeneous catalyst.Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Specifications

CAS 1070-89-9
Density 0.904 g/mL at 25°C
Molecular Formula C6H18NNaSi2
Linear Formula [(CH3)3Si]2NNa
MDL Number MFCD00009835
Quantity 4 x 100 mL
Synonym Hexamethyldisilazane sodium salt solution
Molecular Weight (g/mol) 183.37 g/mol
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