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Medchemexpress LLC Sodium dichloroacetate | 2156-56-1 | MFCD00070489 | 99.8% | 150.92 | C2HCl2NaO2 | 200mg
SDP

Supplier:  Medchemexpress LLC HYY0445A200MG

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Sodium dichloroacetate is an orally active pyruvate dehydrogenase kinase (PDK) inhibitor Sodium dichloroacetate also stimulates pyruvate dehydrogenase (PDH) activity and works as a Na -K -2Cl cotransporter (NKCC) inhibitor Sodium dichloroacetate prevents the phosphorylation of the E1 subunit of PDC promoting the entry of pyruvate into the mitochondria for oxidative metabolism reducing lactate production and simultaneously increasing the production of reactive oxygen species (ROS) Sodium dichloroacetate inhibits tumor cell proliferation and induces apoptosis Sodium dichloroacetate is promising for research of cancers[1][2]

Catalog No. 50-002-70202


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