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Medchemexpress LLC Sodium orthovanadate | 13721-39-6 | 99.4% | 500 MG
Supplier: Medchemexpress LLC HYD0852500MG
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases, and ATPases, acting as a phosphate analogue. It can alter phosphorylation status and inhibit activation pathways during cerebral ischemia. For maximum phosphatase inhibitory activity, it requires a specific activation protocol involving dissolution, pH adjustment, and heating.
- Inhibits protein tyrosine phosphatases, alkaline phosphatases, and ATPases.
- Acts as a phosphate analogue.
- Can alter phosphorylation status of ASK1 and PTEN.
- Inhibits ASK1 activation via PI3-K/Akt.
- Requires specific activation protocol for maximum phosphatase inhibitory activity.
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