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Apexbio Technology LLC Sodium Picosulfate 1mL DMSO
Supplier: Apexbio Technology LLC B20275.1
Sodium picosulfate is an organic stimulant laxative widely utilized to investigate bowel motility and electrolyte balance Its pharmacological activity involves inhibition of fluid and electrolyte absorption alongside enhancement of their secretion in the intestinal lumen thus promoting bowel evacuation In vitro studies evaluating human rat and rabbit liver cell cultures showed sodium picosulfate interaction with hepatic cells notably rabbit hepatocytes demonstrated higher sensitivity reflected by decreased cellular protein content at concentrations in the g/ml range Clinical research supports the utility of sodium picosulfate in experimental constipation models including drug-induced and chronic constipation settings allowing assessment of bowel function and symptoms such as abdominal distension and stool consistency
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