AdipoGen Sodium salicylate

Supplier:  AdipoGen CDXS0145G100

Chemical. CAS 54-21-7. Formula C7H5O3 . Na. MW BD9837. Sodium salicylate is a metabolite of aspirin. It is a cell-permeable, non-steroidal anti-inflammatory agent NSAID that interferes with TNF-induced NF-kappaB activation by inhibiting phosphorylation and subsequent degradation of the IkappaB-alpha protein. It selectively inhibits TNF-induced activation of p42 ERK2 and p44 ERK1 MAP kinases and TNF-induced activation of JNK. It induces apoptosis via p38 kinase activation and inhibits COX-2 and inducible NOS iNOS transcription dependent on the experimental setup. It is commonly used for its antipyretic, anti-oxidant, neuroprotective, anti-inflammatory, anti-cancer and analgesic properties.

Catalog No. 50-256-0058