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Sodium Valproate , MP Biomedicals, LLC

Catalog No. MP215206480 Shop All MP Biomedicals, Inc Products
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100 g
Packaging:
Glass
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MP215206480 100 g Glass
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Catalog No. MP215206480 Supplier MP Biomedicals, Inc Supplier No. 0215206480
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Description

Sodium Valproate is a branched chain fatty acid which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.

  • Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3 α and GSK-3β
  • Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells
  • In animal studies, Valproic Acid has been observed to reduce tumor growth and metastasis formation
  • Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase
  • This compound is also an inhibitor of the CYP2C9 enzyme
  • Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1069-66-5
Molecular Formula C8H15NaO2
Molecular Weight (g/mol) 166.20
InChI Key AEQFSUDEHCCHBT-UHFFFAOYSA-M
Synonym sodium valproate, sodium 2-propylpentanoate, valproate sodium, valproic acid sodium salt, eurekene, labazene, orfiril, epilim, valproic acid sodium, valerin
PubChem CID 16760703
ChEBI CHEBI:9925

Specifications

Color White
Packaging Glass
Quantity 100 g
Percent Purity 100.8

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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