Sodium Valproate , MP Biomedicals, LLC

Description

Sodium Valproate is a branched chain fatty acid which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.

• Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3 α and GSK-3β
• Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells
• In animal studies, Valproic Acid has been observed to reduce tumor growth and metastasis formation
• Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase
• This compound is also an inhibitor of the CYP2C9 enzyme
• Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder

Specifications

Chemical Identifiers

• CAS: 1069-66-5
• Molecular Formula: C8H15NaO2
• Molecular Weight (g/mol): 166.20
• InChI Key: AEQFSUDEHCCHBT-UHFFFAOYSA-M
• Synonym: sodium valproate, sodium 2-propylpentanoate, valproate sodium, valproic acid sodium salt, eurekene, labazene, orfiril, epilim, valproic acid sodium, valerin
• PubChem CID: 16760703
• ChEBI: CHEBI:9925

• Color: White
• Packaging: Glass
• Quantity: 100 g
• Percent Purity: 100.8

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov