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Apexbio Technology LLC Solifenacin succinate 242478-38-2 10mM (in 1mL DMSO)
SDP

Catalog No. 5000063758
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Solifenacin succinate (CAS 242478-38-2) is a selective muscarinic M3 receptor antagonist derived from tetrahydroisoquinoline and quinuclidine It primarily exerts its effect by competitively blocking acetylcholine binding at M3 receptors thereby attenuating muscarinic-mediated intracellular calcium mobilization In receptor binding assays solifenacin displays highest affinity for human M3 receptors (Ki 12 nM) It also selectively inhibits carbachol-induced contractions in isolated rat bladder tissues Consequently solifenacin succinate is frequently employed in biomedical research focused on lower urinary tract physiology and disorders associated with bladder hyperactivity

Catalog No. 50-000-63758 Supplier Apexbio Technology LLC Supplier No. B16145.1
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Solifenacin succinate (CAS 242478-38-2) is a selective muscarinic M3 receptor antagonist derived from tetrahydroisoquinoline and quinuclidine It primarily exerts its effect by competitively blocking acetylcholine binding at M3 receptors thereby attenuating muscarinic-mediated intracellular calcium mobilization In receptor binding assays solifenacin displays highest affinity for human M3 receptors (Ki 12 nM) It also selectively inhibits carbachol-induced contractions in isolated rat bladder tissues Consequently solifenacin succinate is frequently employed in biomedical research focused on lower urinary tract physiology and disorders associated with bladder hyperactivity

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