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Medchemexpress LLC Solithromycin | 760981-83-7 | 99.85% | 845.01 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY17593100MG

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Solithromycin is an orally bioavailable, effective antimicrobial agent. It inhibits cell viability, protein synthesis, and growth rate against various bacteria, including *Streptococcus pneumonia*, *Staphylococcus aureus*, and *Haemophilus influenzae*. This macrolide binds to the large 50S subunit of the ribosome, thereby inhibiting protein biosynthesis.

  • Orally bioavailable and effective antimicrobial agent
  • Inhibits protein synthesis by binding to the large 50S ribosomal subunit
  • Macrolide
  • Inhibits TNFa and CXCL8 release
  • Reduces MMP9 activity
  • Suppresses lipopolysaccharide-induced TNFa release and PMA-induced MMP9 activity
  • Does not affect cell viability in monocytic U937 and PBMC cells
  • Inhibits inflammatory cells accumulation and pro-MMP9 production in cigarette smoke-exposed mice
  • Inhibits cigarette smoke-induced neutrophilia and pro-MMP9 production

Catalog No. 50-003-87445


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