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Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.97% | 681.49 | 10 MM 1 ML
Supplier: Medchemexpress LLC HY1658210MM/1ML
Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist, inhibiting the Hedgehog (Hh) pathway. It has demonstrated antitumor activity in medulloblastoma models and can reduce chronic myeloid leukemia (CML) stem cells.
- Potent and selective Smo antagonist
- Inhibits Hedgehog pathway signaling
- Reduces expression of downstream signaling targets
- Demonstrates dose-related antitumor activity
- Reduces chronic myeloid leukemia stem cells
- Associated with numerous clinical trials
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