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Medchemexpress LLC Sonidegib diphosphate | 1218778-77-8 | 99.97% | 681.49 | 10 MM 1 ML
SDP

Catalog No. 5000391796
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Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist, inhibiting the Hedgehog (Hh) pathway. It has demonstrated antitumor activity in medulloblastoma models and can reduce chronic myeloid leukemia (CML) stem cells.

  • Potent and selective Smo antagonist
  • Inhibits Hedgehog pathway signaling
  • Reduces expression of downstream signaling targets
  • Demonstrates dose-related antitumor activity
  • Reduces chronic myeloid leukemia stem cells
  • Associated with numerous clinical trials

Catalog No. 50-003-91796 Supplier Medchemexpress LLC Supplier No. HY1658210MM/1ML
May include imposed supplier surcharges.
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Sonidegib diphosphate is a potent and selective Smoothened (Smo) antagonist, inhibiting the Hedgehog (Hh) pathway. It has demonstrated antitumor activity in medulloblastoma models and can reduce chronic myeloid leukemia (CML) stem cells.

  • Potent and selective Smo antagonist
  • Inhibits Hedgehog pathway signaling
  • Reduces expression of downstream signaling targets
  • Demonstrates dose-related antitumor activity
  • Reduces chronic myeloid leukemia stem cells
  • Associated with numerous clinical trials

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