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Abcam Sonidegib (NVP-LDE225, Erismodegib), smoothened (Smo) antagonist, 10MG

Catalog No. 502672005
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MW 485.5 Da. Potent and selective Smoothened antagonist. Blocks Hedgehog signaling pathway activity (IC₅₀ = 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays. Anti-tumor activity in mouse medulloblastoma allograft model.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-267-2005 Supplier Abcam Supplier No. AB26987610MG
May include imposed supplier surcharges.
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MW 485.5 Da. Potent and selective Smoothened antagonist. Blocks Hedgehog signaling pathway activity (IC₅₀ = 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays. Anti-tumor activity in mouse medulloblastoma allograft model.

The product is subject to the following: Abcam Restricted Use Statement

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