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Abcam Sonidegib (NVP-LDE225, Erismodegib), smoothened (Smo) antagonist, 100MG
Supplier: Abcam AB269876100MG
MW 485.5 Da. Potent and selective Smoothened antagonist. Blocks Hedgehog signaling pathway activity (IC₅₀ = 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays. Anti-tumor activity in mouse medulloblastoma allograft model.
The product is subject to the following: Abcam Restricted Use Statement
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