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Medchemexpress LLC Sophoricoside | 152-95-4 | 432.38 | 500 MG
Supplier: Medchemexpress LLC HYN0423500MG
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica with anti-inflammatory, anti-cancer, and immunosuppressive effects. It has been shown to significantly inhibit histamine release and reduce levels of inflammatory cytokines like TNF-α, IL-8, and IL-6 in vitro. In vivo, it can reduce scratching behaviors and recover atopic dermatitis in mice.
- Inhibits PMACI-induced histamine release.
- Reduces TNF-α, IL-8, and IL-6 levels.
- Inhibits Rel/p65 levels in the nucleus.
- Reduces enhanced caspase-1 activity.
- Decreases scratching behaviors.
- Recovers atopic dermatitis in mice.
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