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Apexbio Technology LLC Sorafenib(Synonyms: Nexavar, BAY 43-9006, BAY-43-9006, BAY439006, Sorafenib Tosylate, BAY-545-9085), 10mM (in 1mL DMSO), CAS: 284461-73-0.

Supplier: Apexbio Technology LLC A30095.1
Sorafenib (CAS 284461-73-0) is an orally bioavailable small molecule inhibitor targeting multiple kinases including Raf kinase as well as receptor tyrosine kinases such as VEGFR2 PDGFR FLT3 Ret and c-Kit By inhibiting Raf signaling pathways sorafenib suppresses tumor cell proliferation induces apoptosis and disrupts tumor angiogenesis In vitro studies demonstrate that sorafenib effectively inhibits Raf-mediated signaling cascades and blocks the proliferation of tumor cells Sorafenib serves as an important research tool in the study of cancer biology particularly in investigating antiangiogenic and antiproliferative mechanisms in various tumor models
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