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Medchemexpress LLC Sorafenib-d3 (Donafenib; Bay 43-9006-d3) | 1130115-44-4 | 99.57% | 467.84 | 25 MG
Supplier: Medchemexpress LLC 25MGHY10201S
Sorafenib-d3 (Donafenib) is a deuterated compound of Sorafenib, recognized as the first deuterium-generation tumor suppressor small molecule. Sorafenib itself is a multikinase inhibitor with IC50s of 6 nM for Raf-1, 20 nM for B-Raf, and 22 nM for VEGFR-3. This compound is intended for research use only. Potential advantages of deuterated compounds like Sorafenib-d3 include:
- Extends the in vivo half-life.
- Improves oral bioavailability.
- Enhances metabolic characteristics.
- Improves drug safety.
- Preserves therapeutic properties.
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