Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502563110

AdipoGen Sortilin h mAb recblock
SDP

Supplier:  AdipoGen AG27B7000PFC100

Encompass_Preferred

Recombinant Antibody. Recognizes and binds to human sortilin. Source CHO cells. Isotype Human IgG1kappa. Immunogen Recombinant human Sortilin. Applications FUNC Blocking. Sortilin is a type I transmembrane multiligand receptor that is a member of the Vacuolar protein sorting 10 protein Vps10p domain receptor family. It is a 95 kDa protein, ubiquitously expressed, although most abundantly expressed in neurons, hepatocytes, adipocytes and white blood cells including macrophages. Sortilin is synthesized as a propeptide in the endoplasmic reticulum ER and processed to its mature form by furin-mediated cleavage in the trans-Golgi network. The SORL1 gene is one of the strongest genetic risk factors for Alzheimers disease and is associated with frontotemporal dementia. The primary function of sortilin is trafficking proteins from the Golgi to secretory vesicles and endolysosomal compartments.

Catalog No. 50-256-3110


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.