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Enzo Life Sciences SOS-1 (human) (1149-1158) (1mg)
Supplier: Enzo Life Sciences BMLP3050001
SH3 binding sequence of guanine nucleotide exchange factor hSOS which is a ligand for the adaptor protein Grb2 SH3 domain. Blocks SOS/Grb2 interaction and thereby prevents Ras activation via receptor protein tyrosine kinases. Km=5.6 µM for N-terminal SH3 of Grb2. Alternative name: SOS-1 (human) N10 SH3 binding domain, Ras inhibitory peptide. Purity: ≥98%. Solubility: Soluble in Water. Long Term Storage: -20°C.
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