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Medchemexpress LLC Sotuletinib hydrochloride | 2222138-31-8 | 99.4% | 50 MG
SDP

Catalog No. 5000339293
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Sotuletinib (BLZ945) hydrochloride is a potent, selective, orally active, and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, demonstrating over 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. It is utilized for microglia depletion and research in tumor and CNS-related diseases.

  • Potent, selective, and orally active CSF-1R (c-Fms) inhibitor
  • Brain-penetrant properties
  • Exhibits over 1,000-fold selectivity against closest receptor tyrosine kinase homologs
  • Useful for microglia depletion studies
  • Applied in tumor and CNS-related disease research
  • Inhibits CSF-1-dependent proliferation in bone marrow-derived macrophages
  • Decreases CSF-1R phosphorylation

Catalog No. 50-003-39293 Supplier Medchemexpress LLC Supplier No. HY12768A50MG
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Sotuletinib (BLZ945) hydrochloride is a potent, selective, orally active, and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, demonstrating over 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. It is utilized for microglia depletion and research in tumor and CNS-related diseases.

  • Potent, selective, and orally active CSF-1R (c-Fms) inhibitor
  • Brain-penetrant properties
  • Exhibits over 1,000-fold selectivity against closest receptor tyrosine kinase homologs
  • Useful for microglia depletion studies
  • Applied in tumor and CNS-related disease research
  • Inhibits CSF-1-dependent proliferation in bone marrow-derived macrophages
  • Decreases CSF-1R phosphorylation

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