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Medchemexpress LLC SP-141 | 1253491-42-7 | 98.9% | 324.38 | 25 MG
SDP

Catalog No. 5000345742
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SP-141 is a specific inhibitor of MDM2. It promotes MDM2 auto-ubiquitination and degradation. This compound may be used for the research of pancreatic cancer and breast cancer cells.

  • Specific inhibitor of MDM2.
  • Promotes MDM2 auto-ubiquitination and degradation.
  • Potential for research in pancreatic cancer and breast cancer cells.
  • Inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM in a p53-independent manner.
  • Shows selective cytotoxicity for cancer cells.
  • Induces MDM2 auto-ubiquitination and proteasomal degradation.
  • Suppresses pancreatic tumor growth in both xenograft and orthotopic mouse models.
  • Reduced tumor volume by 75% in a pancreatic xenograft model without significant differences in body weight in one study.

Catalog No. 50-003-45742 Supplier Medchemexpress LLC Supplier No. 25MGHY110182
May include imposed supplier surcharges.
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SP-141 is a specific inhibitor of MDM2. It promotes MDM2 auto-ubiquitination and degradation. This compound may be used for the research of pancreatic cancer and breast cancer cells.

  • Specific inhibitor of MDM2.
  • Promotes MDM2 auto-ubiquitination and degradation.
  • Potential for research in pancreatic cancer and breast cancer cells.
  • Inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM in a p53-independent manner.
  • Shows selective cytotoxicity for cancer cells.
  • Induces MDM2 auto-ubiquitination and proteasomal degradation.
  • Suppresses pancreatic tumor growth in both xenograft and orthotopic mouse models.
  • Reduced tumor volume by 75% in a pancreatic xenograft model without significant differences in body weight in one study.

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