Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC SP-141 | 1253491-42-7 | 98.9% | 324.38 | 25 MG
Supplier: Medchemexpress LLC 25MGHY110182
SP-141 is a specific inhibitor of MDM2. It promotes MDM2 auto-ubiquitination and degradation. This compound may be used for the research of pancreatic cancer and breast cancer cells.
- Specific inhibitor of MDM2.
- Promotes MDM2 auto-ubiquitination and degradation.
- Potential for research in pancreatic cancer and breast cancer cells.
- Inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM in a p53-independent manner.
- Shows selective cytotoxicity for cancer cells.
- Induces MDM2 auto-ubiquitination and proteasomal degradation.
- Suppresses pancreatic tumor growth in both xenograft and orthotopic mouse models.
- Reduced tumor volume by 75% in a pancreatic xenograft model without significant differences in body weight in one study.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?