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Medchemexpress LLC (SP-4-2)-diamminetrans-dioxo(tetrahydro-2H-pyran-4,4-diyl)dihydrogen phosphate platinum | 1339960-28-9 | 95.0% | 485.23 | 100 MG
Supplier: Medchemexpress LLC HY10914610MG
Imifoplatin (PT-112) is a platinum-based active molecule, categorized within the phosphaplatins family. It is known for its ability to induce apoptosis and demonstrates significant antitumor activity. This compound has been investigated for its potential in treating various cancers, showing promising results in both *in vitro* and *in vivo* studies, particularly in inhibiting proliferation and inducing apoptosis in cancer cell lines.
- Induces apoptosis.
- Exhibits antitumor activity.
- Shows dose-dependent proliferation inhibition in cancer cells.
- Significantly increases mitochondrial reactive oxygen species (mtROS).
- Demonstrates potent antitumor immune effects in xenograft models.
- Shows synergistic antitumor effects when combined with immune checkpoint blockers.
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