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Enzo Life Sciences Sp-5,6-Dichloro-cBIMPS (1mg). CAS: 120912-54-1
Supplier: Enzo Life Sciences BMLCN1200001
A cAMP analog which is a potent and specific activator of cAMP-dependent protein kinase. It is cell permeable and is not significantly hydrolyzed by type I, II or III phosphodiesterases. It may be used to distinguish the cAMP- versus the cGMP-mediated signal transduction pathways. Surpasses the widely used but problematic dibutyryl-cAMP (BML-CN125) or 8-CPT-cAMP (BML-CN130). Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (167 mM), dimethyl formamide (167 mM), 96 % ethanol (167 mM), methanol (25 mM), water (25 mM) and aqueous buffers such as phostphate buffered saline (pH 7.4; 1.4 mM), 25 mM TRIS (pH 7.4-; 25 mM), 25 mM HEPES (pH 7.2; 35.7 mM) or Na2HPO4. Long Term Storage: -20°C.
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