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Apexbio Technology LLC Spectinomycin (hydrochloride hydrate)(Synonyms: Spectinomycin hydrochloride hydrate, Actinospectacin, Trobicin, Spectam), 1g, CAS: 22189-32-8.
Supplier: Apexbio Technology LLC C56211000
Spectinomycin (hydrochloride hydrate CAS 22189-32-8) is an aminocyclitol antibiotic derived from Streptomyces spectabilis targeting bacterial protein synthesis by interacting specifically with the 30S ribosomal subunit Binding near helix 34 of the 16S rRNA spectinomycin inhibits protein translation by preventing elongation factor G-mediated translocation of peptidyl-tRNA from the ribosomal A-site to the P-site Resistance mutations to spectinomycin align closely with those conferring streptomycin resistance confirming the 30S subunit as its primary target It is applied in biomedical research to study ribosomal function antibiotic binding dynamics and bacterial resistance mechanisms
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