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Cayman Chemical SpGunosIn5O 1thIotrIp 2.7mg

Supplier: Cayman Chemical 386862.7 MG

An FLT3 inhibitor inhibits wild-type FLT3D835Y and FLT3-ITD (IC50s 13 8 and 3 nM respectively) suppresses the growth of MV4-11 AML cells that express FLT3-ITD (GI50 7 nM) induces cell cycle arrest at the G1 phase and apoptosis in the same cells reduces intratumor FLT3-ITD autophosphorylation in a MV4-11 mouse xenograft model at 10 mg/kg
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