Cayman Chemical Sphingosine (d18:1), 123-78-4, 10 mg
Manufacturer: Cayman Chemical 1000790710
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits PKC and phosphatidic acid phosphohydrolase, whereas it activates PLD and DAG kinase. Phosphorylation of sphingosine by SPHK 1 and SPHK 2 produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
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